Actively Recruiting

Age: 0 - 18Years
All Genders
Healthy Volunteers
NCT04478006

Advanced Translational Research on Childhood Leukemia

Led by Chinese University of Hong Kong · Updated on 2026-02-03

300

Participants Needed

1

Research Sites

413 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Prognosis of children with leukemia, the most common pediatric cancer, has improved markedly. Yet, relapse still occurs in 15-40% of patients with a probability of survival of \<50%, which is unlikely to be boosted by intensification of standard chemotherapy due to overwhelming toxicity. The advent of effective and safe targeted therapies for high-risk cases is therefore imperative. This study constitutes two research projects aiming at driving therapeutic advances.

CONDITIONS

Official Title

Advanced Translational Research on Childhood Leukemia

Who Can Participate

Age: 0 - 18Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of acute lymphoblastic leukemia (ALL) or
  • Diagnosis of acute myeloid leukemia (AML) or
  • Diagnosis of mixed phenotype acute leukemia (MPAL) or
  • Diagnosis of juvenile myelomonocytic leukemia (JMML) or
  • Diagnosis of myelodysplastic syndromes (MDS) or
  • Being a normal bone marrow donor
Not Eligible

You will not qualify if you...

  • Unable to understand English or Chinese
  • Patient or parent refuses to participate

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hong Kong Children Hospital

Hong Kong, Hksar, China

Actively Recruiting

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Research Team

K

Kathy Chan, Ph. D.

CONTACT

K

Kam Tong Leung, Ph. D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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