Actively Recruiting

Phase Not Applicable
Age: 6Years - 12Years
All Genders
ID07047430

The Airports, Air Quality, and Asthma (AAA) Study Evaluating HEPA Air Cleaners for Pediatric Asthma Near Seattle-Tacoma International Airport

Led by University of Washington · Updated on 2025-07-02

60

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Children with asthma living near airports are at higher risk of serious asthma attacks due to indoor air pollution from roadway and aircraft traffic. This research evaluates whether using portable air cleaners with HEPA filters can improve indoor air quality and reduce asthma symptoms in these vulnerable children. The study involves collaboration with community health workers (CHWs) delivering asthma education in South King County, Washington, aiming to recruit about 60 children aged 6 to 12 years with asthma. Participants are randomly assigned to one of two groups: one receives a true HEPA air cleaner, and the other receives a sham air cleaner lacking the HEPA and carbon filters but with a pre-filter. Both devices are installed in the child's bedroom during a baseline home visit. The intervention lasts for three months, during which indoor air quality and asthma health are repeatedly assessed. The study integrates CHWs into multiple aspects of the trial, including education and community engagement. Throughout the three-month study and follow-up, caregivers complete weekly questionnaires tracking asthma symptoms and healthcare use. Air quality monitors record indoor pollution levels. Researchers measure outcomes such as weekly symptom days and changes in asthma control scores. The study's findings will help determine if adding HEPA air cleaners to existing asthma education programs benefits children exposed to airport-related pollution.

CONDITIONS

Brief Title

The Airports, Air Quality, and Asthma (AAA) Study

Who Can Participate

Age: 6Years - 12Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Child is 6-12 years old with a healthcare provider-diagnosed asthma.
  • Caregiver is comfortable participating in all study activities in English.
  • Caregiver is familiar with the child's daily asthma health.
  • Residence within 10 miles of Seattle-Tacoma International Airport by zip code.
  • Child lives in caregiver's home at least five nights a week and has no plans to move in the next three months.
Not Eligible

You will not qualify if you...

  • Child has severe asthma defined by daily symptoms over the past 14 days or two or more hospitalizations for asthma in the past 12 months.
  • Households with multiple individuals eligible for the King County CHW Asthma Program or with severe asthma are excluded.

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - 3 months

Participants have a portable air cleaner installed in their child's bedroom. The intervention group receives a unit with a HEPA filter, while the control group receives a similar unit without the HEPA and carbon filters.

1 baseline home visit and weekly questionnaire submissions

Monitoring

Duration - 3 months

Participants complete weekly questionnaires tracking asthma symptoms and health care utilization. Indoor and outdoor air quality is monitored throughout the study period.

Weekly questionnaires

Trial Site Locations

Total: 1 location

1

University of Washington

Seattle, Washington, United States, 98195

Actively Recruiting

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Research Team

C

Christine Loftus, PhD, MPH

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Published Research Related To This Trial

The Airport Air Quality and Asthma (AAA) indoor air intervention trial for children with asthma: Protocol for a community-based study in South King County, Washington State.

Christine T Loftus, Pamela Lim, Jan Capps...

https://pubmed.ncbi.nlm.nih.gov/41310837

The Airport, Air Quality and Asthma (AAA) Indoor Air Intervention Trial for Children with Asthma: Protocol for a Community Based Study in South King County, Washington State.

Christine Loftus, Pamela Lim, Jan Capps...

https://pubmed.ncbi.nlm.nih.gov/41041530