Study of Alveolar Recruitment to Improve Breathing Outcomes During Major Gynecological Cancer Surgery in Obese Women

What this Trial Is About

Researchers are studying the effect of alveolar recruitment strategy on postoperative lung complications in obese patients undergoing major open gynecological cancer surgeries. This study focuses on patients with endometrial or ovarian cancer who receive lung protective ventilation during surgery. The research also aims to assess intraoperative blood flow, breathing mechanics, and length of hospital stay after surgery. Participants will be divided into two groups one group will receive lung protective ventilation combined with alveolar recruitment strategy, and the other group will receive lung protective ventilation without alveolar recruitment. The alveolar recruitment maneuver involves adjusting ventilator settings to increase positive pressure in the lungs during surgery to potentially improve breathing. Ventilation settings include tidal volume based on ideal body weight and positive end-expiratory pressure. During the study, patients will be monitored closely for lung complications within 24 hours after surgery. Researchers will also track blood pressure and breathing parameters during the operation. The length of hospital stay will be recorded to assess recovery. This trial provides detailed monitoring of respiratory and hemodynamic function during and after surgery to understand the effects of the recruitment strategy.

Alveolar Recruitment in Obese Patients in Major Gynaecological Cancer Surgery