Actively Recruiting

Age: 21Years - 80Years
All Genders
NCT04185844

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Led by University of New Mexico · Updated on 2025-05-15

500

Participants Needed

3

Research Sites

408 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. To address this burden of CKD in AI communities Investigators formed a consortium of investigators with extensive experience in conducting research of chronic diseases including diabetes, cardiovascular and kidney disease in AIs of Southwestern US. The proposed CRIC ancillary cohort study of 500 AIs (AI-CRIC) will rapidly improve our understanding of both potential risk factors for CKD progression, as well as the scope of this disease among AIs. This study leverages the current CRIC study and incorporates the planned activities of the next phase of the study - "CRIC 2018" - by implementing contemporary CRIC protocols for kidney and cardiovascular measurement and outcomes.

CONDITIONS

Official Title

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Who Can Participate

Age: 21Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • eGFR between 61 and 80 with microalbuminuria over 30, or eGFR 60 or less regardless of microalbuminuria
Not Eligible

You will not qualify if you...

  • Unable or unwilling to provide informed consent
  • Life expectancy less than 3 years
  • Institutionalized individuals
  • End-stage renal disease or renal transplant
  • Renal cancer
  • Myeloma
  • Immunosuppression
  • Polycystic kidney disease
  • Currently participating in any clinical trial
  • Current pregnancy
  • Current incarceration
  • Unlikely or unable to participate in study procedures as judged by study staff

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

NIDDK-Phoenix Epidemiology and Clinical Research

Phoenix, Arizona, United States, 85016

Not Yet Recruiting

2

First Nations Community Health Source

Albuquerque, New Mexico, United States, 87108

Actively Recruiting

3

Zuni Health Initiative Center

Black Rock, New Mexico, United States, 87327

Actively Recruiting

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Research Team

M

Mark L Unruh, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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