Actively Recruiting
Analgesia-First Sedation in Trauma Patients
Led by MemorialCare Health System · Updated on 2025-07-09
170
Participants Needed
1
Research Sites
178 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study's aim is to ascertain the best approach for providing sedation and pain management for patients who have sustained trauma and are requiring respiratory support from a mechanical ventilator. The common approach to patients who need mechanical ventilation is to provide continuous drips of sedatives and pain medicine and awaken the patient once a day to check the brain functions. Another approach is to provide pain medicine and reserve sedatives for only a short duration when needed. The difference between approaches has not been studied in Trauma patients.
CONDITIONS
Official Title
Analgesia-First Sedation in Trauma Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Mechanically ventilated with an expected duration of 48 hours or more
- Started continuous sedative and analgesic infusions by the ICU team
- Patient is eligible for weaning from mechanical ventilation
You will not qualify if you...
- Admission after resuscitation from cardiac arrest
- Significant neurological deficit due to a chronic disorder
- History of alcohol dependence or illicit drug abuse
- Received continuous sedative or analgesic infusions before ICU transfer
- Currently receiving neuromuscular blocking agents
- Allergy to midazolam, lorazepam, or propofol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Long Beach Memorial Medical Center
Long Beach, California, United States, 90806
Actively Recruiting
Research Team
M
Maged Tanios, MD, MPH
CONTACT
H
Hyunsoon Park, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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