Actively Recruiting
Anifrolumab Malignancy and Serious Infections Study
Led by AstraZeneca · Updated on 2026-04-23
3195
Participants Needed
4
Research Sites
304 weeks
Total Duration
On this page
Sponsors
A
AstraZeneca
Lead Sponsor
I
IQVIA Pty Ltd
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is an observational study, in which the main research question is to evaluate the risk of malignancies and serious infections among moderate/severe SLE patients who receive anifrolumab compared with a comparable population of moderate/severe SLE patients on standard of care who do not initiate anifrolumab.
CONDITIONS
Official Title
Anifrolumab Malignancy and Serious Infections Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First prescription of anifrolumab during the study period with no prior use before the index date
- At least 12 months of available medical data before the index date
- Age 18 years or older at the index date
- Moderate to severe Systemic Lupus Erythematosus at the index date
- Experienced at least one SLE flare or uncontrolled disease in the 6 months before the index date
You will not qualify if you...
- Any diagnosis of malignancy before the index date
- Diagnosis of HIV/AIDS or congenital immunodeficiency before the index date
- Organ or bone marrow transplant performed before the index date
- Serious infection diagnosed in the 6 months prior to the index date
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Research Site
Copenhagen, Denmark, 23000
Actively Recruiting
2
Research Site
Charenton-le-Pont, France, 94220
Actively Recruiting
3
Research Site
Essen, Germany, 45128
Actively Recruiting
4
Research Site
Barcelona, Spain, 08007
Actively Recruiting
Research Team
A
AstraZeneca Clinical Study Information Center
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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