Actively Recruiting

Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT07397728

" TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus

Led by South Valley University · Updated on 2026-02-09

90

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by diverse clinical manifestations, prominently involving the skin.

CONDITIONS

Official Title

" TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult aged 18-60 years
  • Diagnosed as SLE per 2019 EULAR/ACR classification criteria
  • Presence of at least one cutaneous manifestation (acute, subacute, or chronic)
  • Willing to provide written informed consent for participation and genetic testing
Not Eligible

You will not qualify if you...

  • Overlap autoimmune syndromes (e.g., dermatomyositis, systemic sclerosis)
  • Systemic infection, malignancy, or pregnancy
  • Use of biologic therapy or immunosuppressive pulses within one month

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Qina University hospital, South Valley University Hospital

Qina, South Valley, Egypt

Actively Recruiting

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Research Team

A

Amira Rabea AbuElfadl, MSc

CONTACT

S

Soheir Abdel-hamid Ali, Lecturer

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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" TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus | DecenTrialz