Retrospective analysis of dental implants among United States Air Force basic military trainees.
Shelrethia O Battle-Siatita, Joseph A Bartoloni, Raymond H Hancock...
https://pubmed.ncbi.nlm.nih.gov/19485117Actively Recruiting
Led by Madigan Army Medical Center · Updated on 2024-12-27
150
Participants Needed
1
Research Sites
N/A
Total Duration
M
Madigan Army Medical Center
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
This research aims to study the effects of disinfectant gels on the bacteria inside dental implants, focusing on military personnel who face higher risks of oral injuries that can affect their dental health and readiness. The study evaluates how hydrogen peroxide or chlorhexidine gels inserted into the internal cavity of dental implants may influence implant failure rates, bacterial load, and the types of bacteria present. These infections, such as peri-implant mucositis and peri-implantitis, cause bone loss and inflammation around implants and are common issues that can affect implant success. Participants will be randomly assigned to one of three groups: a control group receiving standard care, a group receiving chlorhexidine gel, or a group receiving hydrogen peroxide gel applied inside the dental implant cavity during implant insertion. The study focuses on early-phase research to assess how these antiseptic treatments impact bacterial presence and implant outcomes over a four-month period after the implant procedure. During the study, participants will be monitored for implant failure, the development of peri-implantitis, bacterial amounts, and changes in the bacterial community at four months post-implant insertion. Researchers will collect data through clinical assessments and microbiome analysis to understand how these treatments affect infection and implant health. The total participation duration includes the initial implant procedure and follow-up evaluations within four months, with the goal of improving dental implant success and military readiness.
CONDITIONS
Antiseptic Effects on the Dental Implant Internal Surface Microbiome
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You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 4 months post dental implant insertion
Participants receive dental implant insertion with either standard care, chlorhexidine, or hydrogen peroxide placed inside the implant's internal cavity to reduce bacterial load and improve implant success.
1 visit for implant insertion and follow-up visits as scheduled up to 4 months
Total: 1 location
1
Madigan Army Medical Center
Tacoma, Washington, United States, 98431
Actively Recruiting
K
Kevin D Smith, DMD
Z
Zachary T Colburn, PhD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
3
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