Actively Recruiting
Antiseptic Effects on the Dental Implant Internal Surface Microbiome
Led by Madigan Army Medical Center · Updated on 2024-12-27
150
Participants Needed
1
Research Sites
170 weeks
Total Duration
On this page
Sponsors
M
Madigan Army Medical Center
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
Soldiers operate in environments that are more likely to lead to oral trauma, risking poor dentition which can directly impact military readiness. Dental restoration can often be accomplished via dental implant insertion. Microbiome-associated complications that result in bone loss, including the micro-leakage of bacterial species proliferating in the dental implant internal cavity, frequently lead to implant failure. Reduction in implant bacterial load may result in a shift of the composition of the microbiome in favor of less pathogenic species, potentially improving dental implant success rates, reducing surgical revisions, and associated cost savings. This study aims to determine how disinfectant gel (hydrogen peroxide or chlorhexidine) insertion into dental implant internal cavities affects implant failure rates, bacterial load and microbiome composition.
CONDITIONS
Official Title
Antiseptic Effects on the Dental Implant Internal Surface Microbiome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Active duty military
- Between 18 and 55 years old
- At least 6 months remaining at local duty station
You will not qualify if you...
- Current tobacco user
- Taking medications that affect soft tissue or bone healing
- Having a metabolic disorder that affects soft tissue or bone healing
- Having active periodontal disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Madigan Army Medical Center
Tacoma, Washington, United States, 98431
Actively Recruiting
Research Team
K
Kevin D Smith, DMD
CONTACT
Z
Zachary T Colburn, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
3
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