Observing Effects of Antithrombotic Drugs on Ischemic Stroke Patients Over 40 with Brain Microbleeds

What this Trial Is About

This research aims to observe the effects of different antithrombotic drugs on patients over 40 years old who have had an ischemic stroke and also have cerebral microbleeds. Cerebral microbleeds are small brain vessel injuries causing deposits of blood breakdown products, which can increase the risk of brain bleeding. The study also uses proteomic methods to find blood markers that might predict how these patients will recover. Participants will be observed for one year after their stroke while using various antithrombotic drugs, which are commonly prescribed to prevent further strokes but may raise the risk of brain bleeding in these patients. The study involves tracking changes in cerebral microbleeds and stroke recurrence, along with analyzing blood samples to identify proteins linked to patient outcomes. During the one-year study period, participants will have their brain microbleeds monitored and stroke recurrence rates recorded. Blood tests will be done to explore protein markers that could help predict prognosis. The main outcome measured is the increase in cerebral microbleeds one year after stroke onset, with secondary outcomes including stroke recurrence and incidence of brain hemorrhage. Safety and progress will be closely followed throughout the study.

Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds