Actively Recruiting

All Genders
NCT05715203

Aortic Stiffness in Patients With Genetic Aortopathies

Led by IRCCS Policlinico S. Donato · Updated on 2025-09-10

250

Participants Needed

1

Research Sites

150 weeks

Total Duration

On this page

Sponsors

I

IRCCS Policlinico S. Donato

Lead Sponsor

I

Istituto Auxologico Italiano

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to study arterial stiffness in patients with thoracic ascending aortic aneurysms (TAA), either syndromic or non-syndromic. The main questions it aims to answer are: * Stratification of aortic risk based on arterial stiffness; Compare measurements with morphological and haemodynamic features of the ascending thoracic aorta. Participants will be asked to undergo non-invasive evaluation of blood pressure and arterial stiffness.

CONDITIONS

Official Title

Aortic Stiffness in Patients With Genetic Aortopathies

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subjects with ascending aortic aneurysm, either syndromic or non-syndromic
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Patients with early menopause and/or osteoporosis, rheumatic heart disease, and active malignant tumors
  • Patients with acute and chronic inflammatory conditions such as chronic liver disease, chronic renal insufficiency, and thyroid diseases
  • Patients positive for HIV, HCV, HBsAg, or SARS-CoV-2
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Policlinico San Donato

San Donato Milanese, Lombardy, Italy, 20097

Actively Recruiting

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Research Team

A

Alessandro Pini, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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