Actively Recruiting

Phase 4
Age: 21Years +
All Genders
NCT07384403

Application of Topical Oxygen Therapy Around Customized Healing Collar

Led by Cairo University · Updated on 2026-02-03

6

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The preservation and enhancement of peri-implant soft tissues are essential for the long-term success and esthetic integration of dental implants. Customized healing abutments have been introduced to support individualized soft tissue shaping; however, optimizing soft tissue healing around implants remains a clinical challenge. Oxygen plays a critical role in wound healing by promoting angiogenesis, fibroblast proliferation, and collagen synthesis. Topical oxygen therapy has shown promise in accelerating tissue regeneration, yet its application in oral implantology, particularly in conjunction with customized healing abutments, has not been adequately studied. This study aims to provide clinical evidence regarding the effectiveness of topical oxygen therapy in improving linear and volumetric soft tissue changes around dental implants. The findings may guide clinicians in refining soft tissue management protocols and contribute to establishing evidence-based practices in implant dentistry.

CONDITIONS

Official Title

Application of Topical Oxygen Therapy Around Customized Healing Collar

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 21 years and above
  • Indicated for customized healing collar placement after second-stage surgery
  • Good general health
  • Able and willing to provide written informed consent
  • Committed to follow-up visits
Not Eligible

You will not qualify if you...

  • Individuals below 21 years old
  • Systemic diseases affecting healing
  • Smokers or tobacco users
  • Pregnant or lactating women
  • Medications affecting soft tissue healing
  • Patients undergoing chemotherapy or radiotherapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cairo university

Cairo, Egypt

Actively Recruiting

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Research Team

M

Mulhem ahmed, bachelor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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