Effect of the buccal fat pad in the prevention of zygomatic implant surgery postoperative complications: A pilot study.
S Blanco-Ruiz, P Molinero-Mourelle, M Blanco-Ruiz...
https://pubmed.ncbi.nlm.nih.gov/37330966Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
ID06968780
Buccal Pad of Fat Graft vs. Palatal Rotation Scarf Graft for Soft Tissue Enhancement and Prevention of Dehiscence Around Zygomatic Implants in Patients With Severely Atrophic Maxilla
Led by Cairo University · Updated on 2025-12-12
8
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The trial investigates the use of zygomatic implants to treat patients with severely atrophic upper jaws who cannot receive standard implants due to insufficient bone. The study compares two methods of soft tissue augmentation—buccal fat pad graft and palatal rotation scarf graft—to find which better improves tissue volume, stability, and prevents soft tissue complications around these implants. This research aims to enhance long-term outcomes and reduce complications in challenging oral rehabilitation cases. Participants will receive zygomatic implants placed using the Exteriorized ZAGA approach, either alone or combined with axial implants when bone allows. They will be randomly assigned to receive one of two soft tissue grafts after implant placement: the buccal fat pad graft, known for its stem cell properties and tissue engineering potential, or the palatal rotation scarf graft, which uses well-vascularized palatal tissue to protect mucosal tissues and provide lasting stability and esthetics. During the six-month follow-up, participants will undergo assessments of soft tissue condition and quality around the implants, focusing on peri-implant soft-tissue recessions. Implant survival rates will also be monitored. The study includes regular clinical evaluations to track healing, tissue volume, and implant success, with the total participation lasting at least six months after treatment.
CONDITIONS
Brief Title
Buccal Fat Pad vs. Palatal Rotation Scarf Grafts for Soft Tissue Management Around Zygomatic Implants
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Patient aged 18 years or older who can understand and sign informed consent
- Severely atrophic edentulous upper arch classified as Cawood & Howell class IV, V, or VI
- Severely atrophic edentulous upper arch with inadequate bone in Bedrossian zones II, III, or all three zones
- Good overall health with ASA score I or II
- Highly motivated patient with good oral hygiene compliance
You will not qualify if you...
- Cardiovascular, pulmonary, or systemic conditions preventing surgery under general anesthesia (ASA III or higher)
- Conditions contraindicating implant placement such as head/neck radiation, intravenous bisphosphonates, or uncontrolled diabetes
- Heavy smokers (more than 20 cigarettes daily)
- Psychiatric disorders, severe bruxism, or other parafunctional habits
- Acute maxillary sinus infection or untreated maxillary sinus cyst
- Malignancy or other pathology in the maxilla or zygoma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Single surgical procedure with immediate soft tissue grafting
Participants undergo surgery to place zygomatic implants using the ZAGA approach combined either with a buccal fat pad graft or a palatal rotation scarf graft to enhance soft tissue around the implants and prevent tissue dehiscence.
1 surgical visit (in-person)
Post-operative Follow-up
Duration - Up to 6 months
Participants are monitored to assess soft tissue condition, implant survival, and healing outcomes following the graft and implant placement.
Approximately 4 to 6 follow-up visits (in-person)
Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Giza Governorate, Egypt, 12613
Actively Recruiting
Loading map...
Research Team
K
Khaled M Allam, DDS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here