Actively Recruiting

Age: 0Years - 100Years
All Genders
ID06235619

CT Anatomical Characteristics of the Aortic Arch in Subjects With or Without Aneurysms Requiring Treatment

Led by IRCCS San Raffaele · Updated on 2025-05-02

500

Participants Needed

1

Research Sites

52 weeks

Total Duration

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AI-Summary

What this Trial Is About

Researchers are investigating the anatomical features of the aortic arch, focusing on a common variant called the common origin of the innominate and left carotid artery (CILCA), which has been linked to thoracic aortic disease (TAD). The study aims to compare these anatomical characteristics in people with and without aneurysms, collecting data from five major European cardiovascular centers. This observational study involves analyzing CT scans of the aortic arch from two groups: individuals without aneurysms requiring treatment and those with aneurysms that do require treatment. No interventions or treatments are administered; instead, the study focuses on imaging data to understand differences in aortic arch anatomy. Participants undergo aortic arch CT scans at participating centers, and researchers measure changes and differences in aortic arch anomalies from baseline within 30 days. The study tracks these anatomical features to better understand their relationship to aortic aneurysms and potential risks. The total study period extends until December 2026.

CONDITIONS

Brief Title

Arch Size Study for Anatomical Variations

Who Can Participate

Age: 0Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All patients with aortic arch CT scan at investigating centers
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - 1 day

Participants undergo CT scans to assess anatomical characteristics of the aortic arch.

1 visit (in-person)

Long-term Monitoring

Duration - 30 days

Participants are observed for changes in aortic arch anomalies over 30 days after the CT scan.

Trial Site Locations

Total: 1 location

1

IRCCS San Raffaele Hospital

Milan, Italy, Italy, 20132

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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