Actively Recruiting

Age: 18Years - 90Years
All Genders
Healthy Volunteers
ID06879834

Assessing Artificial Intelligence-based Software Platform for Diabetic Retinopathy Screening

Led by The Filatov Institute of Eye Diseases and Tissue Therapy · Updated on 2025-03-17

200

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

Sponsors

T

The Filatov Institute of Eye Diseases and Tissue Therapy

Lead Sponsor

C

CheckEye LLC

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating an artificial intelligence (AI) software platform called Retina-AI to detect diabetic retinopathy (DR), a complication of diabetes that affects the eyes. The study includes adults aged 18 to 90 who have diabetes mellitus or risk factors for developing diabetes. The goal is to assess the accuracy of this AI tool in identifying DR from eye images. During the study, participants will have fundus photos taken of their eyes using a non-mydriatic fundus camera, which does not require pupil dilation. Two images per eye are captured—one centered on the optic disc and one on the fovea. These images are then uploaded into the AI system, where a neural network processes them to detect signs of diabetic retinopathy. Participants will undergo imaging at the start of the study to provide baseline data. Researchers will measure the accuracy of the AI in detecting DR, including the percentage of invalid images and false positive results. The study is observational and involves no drug treatments. Participants' data will be collected and analyzed to evaluate the AI's performance in screening for diabetic retinopathy.

CONDITIONS

Brief Title

Assessing of Artificial Intelligence-based Software Platform for Diabetic Retinopathy Screening

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Documented diagnosis of diabetes mellitus
  • Understanding of the study and willingness to sign informed consent
  • Age 18 years or older
  • Diagnosis of diabetes: either type 1 diabetes for at least 5 years or type 2 diabetes
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Unable or unwilling to give informed consent
  • Presence of retinal diseases such as age-related macular degeneration, retinal vessel occlusion, coloboma of choroid or optic nerve, retinitis pigmentosa, or angioid streaks
  • Previous treatment (surgery, laser, etc.) for any retinal disease, including age-related macular degeneration or retinal vascular occlusion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo fundus photography using a non-mydriatic fundus camera, and images are processed by an artificial intelligence system to identify diabetic retinopathy in the early stages.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

The Filatov Institute of Eye Diseases and Tissue Therapy

Odesa, Ukraine, 65061

Actively Recruiting

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Research Team

A

Andrii MD Korol, PhD

O

Olha MD Pohosian

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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