Actively Recruiting
Assessing Cancer Treatment Response to Therapy Using 18F-FSPG PET
Led by Guy's and St Thomas' NHS Foundation Trust · Updated on 2025-04-04
32
Participants Needed
1
Research Sites
132 weeks
Total Duration
On this page
Sponsors
G
Guy's and St Thomas' NHS Foundation Trust
Lead Sponsor
K
King's College London
Collaborating Sponsor
AI-Summary
What this Trial Is About
Prospective single centre non-randomised exploratory observational study to measure changes in tumour cellular redox status with 18F-FSPG PET in stage 3 non-small cell lung cancer (NSCLC) and stage 3 and 4 head and neck squamous cell cancer (HNSCC) at baseline and during standard of care treatment, and to compare this with 18F-FDG PET/CT and RECIST 1.1 response at 12 weeks.
CONDITIONS
Official Title
Assessing Cancer Treatment Response to Therapy Using 18F-FSPG PET
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Written informed consent
- Aged 16 or above
- Histologically confirmed head and neck squamous cell cancer or non-small cell lung cancer
- Treatment naive and scheduled to start standard care (chemo)radiotherapy
- Willingness and ability to follow study visits and tests
- Adequate function of all major organs and systems confirmed
You will not qualify if you...
- Pregnant or lactating women
- Uncontrolled medical conditions
- Likely to need palliative radiotherapy within first 12 weeks of treatment
- Life expectancy less than 3 months
- Previous anti-cancer treatment for current cancer
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Guy's and St Thomas' NHS Foundation Trust
London, United Kingdom
Actively Recruiting
Research Team
G
Gark Cook
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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