Actively Recruiting
Assessing MB-Spirit for Psychological Well-being
Led by Sara W Lazar · Updated on 2026-03-20
44
Participants Needed
2
Research Sites
33 weeks
Total Duration
On this page
Sponsors
S
Sara W Lazar
Lead Sponsor
H
Harvard Medical School (HMS and HSDM)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if a new behavioral intervention, MB-Spirit, can improve well-being in stressed adults. The main questions it aims to answer are: 1. Can MB-Spirit improve well-being? 2. What brain changes accompany participation in MB-Spirit? Participants will: 1. Be enrolled in an online course that meets for two hours every week for 8-weeks. 2. Complete questionnaires before and after the course. 3. Complete an MRI scan of their brain before and after the course. Participants will be randomized to either take the course right away, or be put on a wait-list. Those on the wait-list will undergo the testing at 2 timepoints before they start the program.
CONDITIONS
Official Title
Assessing MB-Spirit for Psychological Well-being
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Understands English
- Able to attend all 8 classes
- Able to travel to Boston for MRI scans
You will not qualify if you...
- Claustrophobia
- Pregnancy
- Head trauma
- Metallic implants or devices contraindicating MRI
- Left-handed
- Conditions that alter cerebral blood flow or metabolism (e.g., stroke)
- Current use of psychotropic medications
- Lifetime history of suicidality, homicidality, or self-destructive acts
- Schizophrenia or psychosis
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
149 13th St
Boston, Massachusetts, United States, 02129
Actively Recruiting
2
Charlestown Navy Yard Campus
Boston, Massachusetts, United States, 02129
Not Yet Recruiting
Research Team
S
Sara Lazar, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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