Actively Recruiting
Assessment of Circuit Rebreathing During CPAP Therapy
Led by Brigham and Women's Hospital · Updated on 2025-07-14
13
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
Sponsors
B
Brigham and Women's Hospital
Lead Sponsor
S
Sleep Res, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this research is to better understand how different CPAP mask designs affect airflow and rebreathing of exhaled carbon dioxide (CO₂) during sleep in individuals with obstructive sleep apnea (OSA).
CONDITIONS
Official Title
Assessment of Circuit Rebreathing During CPAP Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Moderate to severe obstructive sleep apnea with apnea-hypopnea index (AHI) greater than 20
- Current or previous use of CPAP therapy
- Maximum CPAP pressure of 13 cmH2O or less if known
- Age between 21 and 70 years
- Body mass index (BMI) between 18 and 40 kg/m2
You will not qualify if you...
- Severe mouth-breathing reported by participant
- Need for nighttime supplemental oxygen or other ventilatory support
- Severe cardiovascular or pulmonary diseases
- Any unstable or acute medical conditions
- Presence of other sleep disorders besides obstructive sleep apnea, such as insomnia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
A
Atqiya Aishah, PhD
CONTACT
S
Scott A Sands, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
OTHER
Number of Arms
11
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