Actively Recruiting
Fibrin Clot Properties and Thrombin Generation in Women After Urogynecological Surgery
Led by Jagiellonian University · Updated on 2025-12-22
60
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
This research aims to evaluate fibrin clot properties and thrombin generation in women who have undergone urogynecological surgery. The study focuses on women with urine incontinence or uterine prolapse who have not responded to pharmacological treatment. It seeks to understand changes in clot permeability and how easily clots are broken down, along with thrombin production, which are important for blood clotting processes. The study involves observing healthy women qualified for urogynecological surgery due to urine incontinence or uterine prolapse. Researchers will determine fibrin clot properties and thrombin generation before and after surgery. This observational study does not involve experimental treatments but focuses on diagnostic testing related to blood clot characteristics. Participants will be monitored from December 2025 until May 2026. During this time, the research team will assess the fibrin clot phenotype and thrombin generation to measure changes related to the surgery. The study aims to gather detailed data on clot behavior and blood clotting factors in this population over a period of several months.
CONDITIONS
Brief Title
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-70 years
- Women with treatment failure from pharmacotherapy for uterine prolapse or urine incontinence
- Qualified for urogynecological surgery due to urine incontinence or uterine prolapse
You will not qualify if you...
- Prolonged thromboprophylaxis treatment
- Planned surgery for reasons other than urine incontinence or uterine prolapse
- Acquired or congenital thrombophilia (blood clotting disorders)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 6 months
Participants undergo determination of fibrin clot properties and thrombin generation before and after urogynecological surgery.
Multiple visits before and after surgery
Duration - December 2025 till May 2026
Participants are monitored for changes in fibrin clot phenotype and thrombin generation following surgery.
Visits occurring over the monitoring period
Trial Site Locations
Total: 1 location
1
Gynecological Endocrinology Department
Krakow, Małopolska, Poland, 31-501
Actively Recruiting
Research Team
M
Magdalena MP Piróg, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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