Evaluation of Venous Insufficiency and Symptom Associations in Women with Lipedema Using Doppler Ultrasonography

What this Trial Is About

Lipedema is a chronic disorder mainly affecting women, characterized by symmetrical fat buildup in the lower limbs, causing pain, tenderness, swelling, and reduced function. This study investigates how venous insufficiencyproblems with blood flow in leg veinsrelates to symptoms like pain and functional limitations in women with lipedema through a cross-sectional controlled observational design. Participants will undergo venous Doppler ultrasonography to assess venous reflux, vein diameter, and affected vein segments in both superficial and deep venous systems. Clinical examination will determine lipedema stage. Additional assessments include measuring pain severity with a Numeric Rating Scale, evaluating lower limb function with the Lower Extremity Functional Scale, assessing quality of life via the SF-12 questionnaire, and measuring leg circumference at standardized points. During the study, participants complete clinical assessments and questionnaires to evaluate symptom severity, function, and quality of life. Researchers will analyze vascular findings alongside clinical data to understand venous involvement in lipedema. The primary outcome is the presence of venous reflux on Doppler ultrasonography. The study is expected to improve diagnosis and management of lipedema, with participation lasting through baseline assessments.

Assessment of Venous Insufficiency and Clinical Features in Lipedema