Actively Recruiting
Association Between Blood Pressure and the Risk of Post-stroke Cognitive Impairment: a Retrospective Cohort Study
Led by First Affiliated Hospital of Chongqing Medical University · Updated on 2024-12-12
600
Participants Needed
1
Research Sites
1 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to explore the relationship between blood pressure and cognitive impairment following a stroke. It includes patients who have been monitored for more than three months after experiencing a stroke. The study uses statistical methods to analyze how blood pressure levels relate to the risk and subtypes of cognitive impairment after stroke. Participants will be patients diagnosed with stroke confirmed by CT or MRI who have completed a Mini-Mental State Examination (MMSE) during hospitalization and have been followed up for at least three months. The study compares groups with and without post-stroke cognitive impairment, defined by specific MMSE score thresholds, using regression analysis and subgroup evaluations. During the study, data such as patient basics, cognitive test scores, and blood pressure levels will be collected and analyzed. The primary measurement is the MMSE score assessed three months after stroke. Researchers will observe the presence and severity of cognitive impairment, examine factors influencing this condition, and ensure data completeness. The total participation time for each patient involves at least a three-month follow-up period after stroke.
CONDITIONS
Brief Title
Association Between Blood Pressure and Risk of PSCI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient diagnosed with stroke by CT or MRI
- Patients completed the MMSE scale at least once during hospitalization
- The follow-up time was more than three months after the stroke occurred
You will not qualify if you...
- Patients with incomplete data or follow-up time less than three months after stroke
- Patients with pre-existing cognitive impairment before stroke
- Patients unable to complete MMSE assessment due to aphasia or other reasons
- Patients with malignant tumors or psychiatric disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to hospitalization period
Participants undergo assessments including the Mini-Mental State Examination (MMSE) at least once during hospitalization to evaluate cognitive function after stroke.
1 visit (in-person)
Duration - More than 3 months
Participants are followed up for more than three months after stroke to observe the relationship between blood pressure and cognitive impairment.
Follow-up visits according to routine clinical care
Trial Site Locations
Total: 1 location
1
First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
Actively Recruiting
Research Team
D
Dingqun Bai
D
Defei Chen
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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