Study of Male Hypogonadism in HIV-Infected and Non-Infected Men Who Have Sex with Men

What this Trial Is About

Researchers are investigating the prevalence of hypogonadism, a condition involving low testosterone, among HIV-infected men who have sex with men MSM. The study compares this group with age-matched MSM who are not infected with HIV. It also aims to identify risk factors for male hypogonadism such as age, duration of HIV infection, other health conditions, body mass index, and antiretroviral therapy use. The relationship between testosterone levels and aspects like sexual function, energy, exercise ability, mood, and bone density will be explored. This observational, cross-sectional study includes two groups HIV-infected MSM and HIV non-infected MSM. Participants will have their serum total and free testosterone levels measured as a diagnostic test. The main outcomes measured during the study period from 2021 to 2030 are symptoms of androgen deficiency and serum free testosterone levels. Participants will be assessed for symptoms related to low androgen and have blood tests for testosterone. The study will also correlate testosterone levels with sexual health, vitality, exercise capacity, mood, and bone mineral density. The study is conducted by the National Taiwan University Hospital and allows healthy volunteers who meet the criteria to participate. The total duration extends through 2030, with ongoing data collection and analysis.

Association Between Human Immunodeficiency Virus (HIV) Infection and Male Hypogonadism