Integrated Cancer Control Program Using Peer Support for Adolescents and Young Adults with HIV in Zambia

What this Trial Is About

Adolescents and young adults living with HIV in Zambia face higher risks of developing cancers such as Kaposi sarcoma, non-Hodgkins lymphoma, and cervical cancer compared to their uninfected peers. This research aims to evaluate peer-to-peer education and support strategies designed to increase early cancer diagnosis and improve treatment completion among this vulnerable group. The ARROW program is being tested against a one-time education campaign to determine its effectiveness in reducing premature cancer mortality in this population. The study compares two approaches the ARROW strategies, which include peer counselors supporting patients, peer-led education sessions for providers, and a collaborative forum involving health administrators and policy makers and a one-time education campaign providing informational brochures alongside usual care. These interventions are implemented within HIV treatment facilities and cancer centers to boost early cancer screening and ensure adherence to recommended treatments. Participants will be followed for up to three years, with key assessments including completion of cancer screenings and treatments within 12 months of enrollment or diagnosis. Researchers will monitor the proportion of patients who complete screenings, initiate and complete cancer treatment, and survive at 12 months. Implementation outcomes like acceptability and cost-effectiveness of the ARROW program will also be studied to support future scaling of these strategies in Zambia and potentially other regions.

AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW)