Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06022913

Behavioural Activation for Bipolar Depression

Led by Reykjavik University · Updated on 2025-04-16

10

Participants Needed

1

Research Sites

110 weeks

Total Duration

On this page

Sponsors

R

Reykjavik University

Lead Sponsor

L

Landspitali University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Bipolar disorder (BD) affects between 1-3% of the world's population. People with BD experience episodes of mania or hypomania and in most cases, they experience periods of depression which can cause difficulties in daily life. Psychological therapies for people experiencing depression without mania or hypomania are widely available, but there is little research into how effective these therapies are for people with BD. Behavioral activation therapy (BA) is based on behavioral theory and has been proven to be an effective treatment for unipolar depression. It helps people re-establish healthier activity patterns and sleep regulation, especially in BD for mood stabilization. BA is theoretically and clinically well matched to the treatment of bipolar depression, but there is still very little research into offering BA to people with BD. The first aim of the current research is to implement BA for people with depression in Bipolar Disorder and study if it is feasible for this patient group. The second aim is to do a pilot study on the effectiveness of the treatment for this patient group. The research will be implemented with people seeking treatment at the specialized service for bipolar disorder at Landspítali University Hospital in Iceland. The participants will receive treatment as usual and the BA will be adjunctive. At least ten people, that are currently experiencing Bipolar Depression and are willing to take part, will receive up to 20 individual therapy sessions of BA that have been adapted for Bipolar Depression (BA-BD), and will complete regular questionnaires and interviews. The study will be a replication study to validate the previous study's findings by Kim, W. et al., 2022 in another setting.

CONDITIONS

Official Title

Behavioural Activation for Bipolar Depression

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scoring in the clinical range on a depression severity self-report (PHQ-9) and meeting diagnostic criteria for depression using DIAMOND
  • Diagnosed with Bipolar I or II Disorder according to DIAMOND
  • Working knowledge of written and spoken Icelandic sufficient to use therapy and complete assessments without a translator
Not Eligible

You will not qualify if you...

  • Current or past learning disability, organic brain change, or substance dependence (drugs or alcohol) that impairs therapy use
  • Current marked risk to self (self-harm or suicide) that cannot be managed in the Bipolar outpatient clinic
  • Lacking capacity to give informed consent
  • Currently receiving other psychosocial therapy for depression or bipolar disorder
  • Presence of another primary area of difficulty requiring intervention focus, such as PTSD or psychosis

AI-Screening

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Trial Site Locations

Total: 1 location

1

Landspitali university hospital

Reykjavik, Iceland, 101

Actively Recruiting

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Research Team

H

Halla Ó Ólafsdóttir, Cand. psych

CONTACT

B

Brynja Bj Magnúsdóttir, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Behavioural Activation for Bipolar Depression | DecenTrialz