Integration of Neural Reward Processing and Appetite-Related Signaling in Obese Females: Evidence From Resting-State fMRI.
Peng Zhang, Yang Liu, Han Lv...
https://pubmed.ncbi.nlm.nih.gov/30653786/Actively Recruiting
Led by Beijing Friendship Hospital · Updated on 2019-09-10
3000
Participants Needed
1
Research Sites
52 weeks
Total Duration
Metabolic surgery is increasingly recognized as a treatment option for patients with severe obesity. This research aims to study the effects and safety of metabolic surgery in Chinese patients with obesity, particularly focusing on its impact on weight loss and obesity-related metabolic conditions such as type 2 diabetes, hypertension, dyslipidemia, sleep apnea, and polycystic ovary syndrome. Larger studies with longer follow-up are needed to better understand these effects. The study collects data on patients undergoing metabolic surgeries like Laparoscopic Sleeve Gastrectomy LSG or Laparoscopic Roux-en-Y Gastric Bypass LRYGB. It tracks outcomes such as weight loss and glycemic control at multiple time points including 1 year, 3 years, 5 years, and 10 years after surgery. Safety is also monitored by recording adverse events within 30 days following surgery. Participants will be followed over time to assess excess weight loss and improvements in metabolic health. Researchers will gather and analyze data on surgery outcomes, complications, and long-term effects. The main outcome measured is excess weight loss one year after surgery, with extended follow-up to evaluate sustained benefits and safety. The study is observational and does not involve assignment to specific treatments by the researchers.
CONDITIONS
Beijing Friendship Hospital Metabolic Surgery Database
Z
Zhongtao Zhang, M.D.
M
Mengyi Li, M.D.
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Beijing Friendship Hospital
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 30 days after surgery
Participants undergo metabolic surgery and receive immediate post-operative care.
Approximately 1 post-operative visit
Duration - Up to 10 years
Participants are followed to assess excess weight loss and glycemic control over time after surgery.
Follow-up visits at 1 year, 3 years, 5 years, and 10 years after surgery
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Peng Zhang, Yang Liu, Han Lv...
https://pubmed.ncbi.nlm.nih.gov/30653786/Han Lv, Mengyi Li, Yang Liu...
https://pubmed.ncbi.nlm.nih.gov/32483745/Beijing Friendship Hospital
Lead Sponsor