Actively Recruiting

Age: 18Years - 120Years
All Genders
ID04570163

Berlin Registry of Right Heart Interventions to Evaluate Outcomes After Catheter-Based Valve Therapies

Led by Charite University, Berlin, Germany · Updated on 2026-03-19

200

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating patients who have undergone interventional treatments for valve diseases affecting the right side of the heart, such as tricuspid and pulmonary valve conditions. The study aims to assess the impact of these various catheter-based therapies, including devices like TriClip and Cardioband, on patient outcomes and to identify which patient subgroups benefit the most. This research is observational and conducted primarily in Berlin and Brandenburg. The treatments studied involve catheter-based procedures that address valve problems in the right heart, focusing on techniques for tricuspid regurgitation and stenosis as well as pulmonary regurgitation and stenosis. These interventions are performed mainly with devices such as TriClip and Cardioband. The study includes follow-up examinations to monitor patients after their valve interventions. Participants will be followed with medical history reviews, laboratory tests, and echocardiograms to evaluate heart function and valve performance. Outcomes measured include overall and cardiovascular mortality, hospitalizations for heart failure, and assessments of heart failure symptoms, heart and valve function, and liver and kidney health. The follow-up period includes evaluations approximately two months after the intervention to track these health indicators and patient status.

CONDITIONS

Brief Title

Berlin Registry of Right Heart Interventions

Who Can Participate

Age: 18Years - 120Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with planned or recent valve interventions of the right heart (tricuspid regurgitation/stenosis, pulmonary regurgitation/stenosis)
  • Age over 18 years
  • Written, documented consent
Not Eligible

You will not qualify if you...

  • Patients in care or unable to consent
  • Patients who are unable to comply with follow-up examinations
  • Patients who are detained in an institution

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Implementation

Duration - N/A

Participants undergo catheter-based valve therapies for right heart valve diseases such as tricuspid regurgitation using devices like TriClip or Cardioband.

Post-operative Follow-up

Duration - 2 months after intervention

Participants are monitored for outcomes including mortality, heart failure hospitalizations, and valve and cardiac function after the intervention.

1 to 2 visits within 2 months after intervention

Trial Site Locations

Total: 1 location

1

Charité - Universitätsmedizin Berlin

Berlin, Germany, 10117

Actively Recruiting

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Research Team

H

Henryk Dreger, Prof. Dr. med.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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