Binocular Amblyopia Treatment Evaluating Enhanced Contrast Protocols in Children Ages 4 to 10 Years

What this Trial Is About

Researchers are evaluating enhanced binocular treatments for children aged 4 to 10 years with amblyopia, a condition that affects vision in one eye. The study compares new treatment protocols designed to extend therapy beyond the usual 4-week period to see if they result in a more complete and stable recovery of vision. This research aims to determine if these alternative methods improve visual acuity and binocular vision compared to the original treatment approach. Participants will play binocular games on a tablet for one hour per day, five days a week, using different contrast increment protocols. The study is a randomized trial with three groups: the original 10% contrast increment, a reduced contrast increment, and no contrast increment. After 8 weeks, children who achieve normal visual acuity will begin stereoacuity training for 4 weeks, while those with remaining vision issues will receive dichoptic movie treatment for an additional 4 weeks. During the 12-week study, children will be assessed at various time points to measure changes in visual acuity, stereoacuity, and suppression. Visual acuity of the amblyopic eye is the primary outcome measured at baseline and 8 weeks. Participants and their families must agree to avoid patching treatments during the study. The research includes regular monitoring and requires children to be able to play the binocular games to participate.

Binocular Amblyopia Treatment