Improving Normal and Amblyopic Vision With Video Games and Perceptual Learning

What this Trial Is About

Amblyopia is a developmental vision problem that reduces how well people see fine details and contrast, leading to vision loss. Researchers are studying how the brain's ability to change (neural plasticity) can help improve vision in both adults and children with amblyopia. The study aims to understand the limits and mechanisms of this brain plasticity using special vision tests. Participants will be randomly assigned to one of three groups. One group will play video games with the amblyopic eye for 1 to 2 hours per session, 4 to 5 times a week, for about 1 to 6 months. Another group will practice visual discrimination tasks such as visual acuity and contrast sensitivity under the same schedule. The third group will use occlusion therapy by covering their dominant eye for similar daily sessions to encourage the use of the weaker eye. During the study, participants will have their vision tested regularly, including measuring visual acuity, stereoacuity, contrast sensitivity, and positional acuity before and after about 9 months of intervention. These measures will help track changes in vision. The research will monitor how each treatment affects visual functions, and participants may be asked to follow the treatment schedules and attend study visits as needed throughout the study duration.

Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games