Actively Recruiting
Biological Bank for Atrial Fibrillation and Stroke
Led by Hospices Civils de Lyon · Updated on 2026-04-17
1000
Participants Needed
5
Research Sites
782 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. This arrhythmia is responsible for 15% of strokes and more than 30% of strokes on people over 65 years. According to studies, 30 to 40% of isolated atrial fibrillations could be familial. Atrial fibrillation has significant genetic heterogeneity. About 40 genes have been identified as potentially involved. Studies have identified genes common to the risk of atrial fibrillation and stroke. Despite the pathophysiology of atrial fibrillation has been intensively and extensively studied for almost a century, there are still many questions. The pathophysiology is not sufficiently understood to allow finding more effective therapies. It is necessary to identify genetic determinants and thus potentially new pharmacological targets more adapted. The establishment of a biological database will test hypotheses concerning the genetic origin and thromboembolic process of atrial fibrillation and associated stroke.
CONDITIONS
Official Title
Biological Bank for Atrial Fibrillation and Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- History of atrial fibrillation (AF) or atrial tachycardia (AT)
- Scheduled for electrophysiological exploration or AF ablation (for certain groups)
- History of stroke
- Age over 80 years with normal heart rhythm and no left atrial enlargement
- Cryptogenic stroke or transient ischemic attack before age 50 with no AF history
You will not qualify if you...
- No history of atrial fibrillation
- Patients who have not signed consent
- Pregnant women (for certain groups)
- Left atrial enlargement greater than 25 cm² or 34 m/m², ejection fraction below 50%
- QRS duration longer than 90 ms on ECG
- Cardiac diseases except hypertension and valvular disease
- History of stroke or transient ischemic attack over age 50
- History of atrial fibrillation in cryptogenic stroke group
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Service neurologie Centre hospitalier Fleyriat
Bourg-en-Bresse, France, 01000
Actively Recruiting
2
Service d'urgences Neurovasculaires - service de neurologie vasculaire , Hôpital Pierre Wertheimer
Bron, France, 69677
Actively Recruiting
3
Service de rythmologie, hôpital cardiologique Louis Pradel
Bron, France, 69677
Actively Recruiting
4
Service de médecine gériatrique Centre hospitalier Lyon Sud, Groupement hospitalier Sud
Pierre-Bénite, France, 69495
Actively Recruiting
5
Hôpital des charpennes
Villeurbanne, France, 69100
Actively Recruiting
Research Team
P
Philippe CHEVALIER, PU-PH
CONTACT
E
Elodie MOREL
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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