What is this study trying to find out about atrial fibrillation and stroke?

This study is investigating the genetic factors and blood clotting processes involved in atrial fibrillation and stroke. Researchers aim to better understand these causes to identify potential new treatment targets. The study is sponsored by Hospices Civils de Lyon and involves collecting biological samples for research.

Who may be eligible for this atrial fibrillation and stroke clinical trial?

Adults aged 18 years or older with a history of atrial fibrillation or stroke, or those over 80 without atrial fibrillation may be eligible. Both men and women can participate, but certain medical conditions or lack of consent may disqualify someone. Please review eligibility criteria for more details.

Is there any cost to participate in this atrial fibrillation and stroke clinical trial?

Study-related care, including blood sample collection and all trial visits, is provided at no cost. However, personal expenses such as travel may vary and are not guaranteed to be covered.

Actively Recruiting

Age: 18Years +

All Genders

ID03611816

Biological Bank for Research on Atrial Fibrillation and Stroke Including Genetic Studies and Patient Data Collection

Led by Hospices Civils de Lyon · Updated on 2026-04-17

1000

Participants Needed

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Atrial fibrillation AF is a common heart rhythm disorder linked to a significant number of strokes, especially in people over 65. This research aims to explore the genetic causes and blood clotting processes related to AF and stroke by creating a biological database. Understanding these genetic factors may help identify new targets for treatments. Participants are grouped based on their AF and stroke history, age, and specific medical procedures. Blood samples are collected to obtain DNA and plasma for genetic studies. The study includes patients with AF with or without stroke, those undergoing certain heart procedures, people over 80 without AF, and individuals with early stroke or transient ischemic attack but no AF. During the study, blood samples are collected and stored for quality analysis up to seven years. Clinical data collection accompanies the biological sampling. Researchers will evaluate the quality and preservation of these samples to support genetic research. Participation involves providing blood samples and medical history information, with ongoing monitoring of sample integrity.

CONDITIONS

Brief Title

Biological Bank for Atrial Fibrillation and Stroke

Who Can Participate

Age: 18Years +

All Genders

Eligibility Criteria

You may qualify if you...

Adults aged 18 years or older
History of atrial fibrillation or atrial tachycardia for Group 1a and 1b
Scheduled electrophysiological exploration or atrial fibrillation ablation for Group 1b
History of stroke along with atrial fibrillation or atrial tachycardia for Group 1c
Patients over 80 years old with normal heart rhythm and no left atrial enlargement for Group 2
History of cryptogenic stroke or transient ischemic attack before age 50 without atrial fibrillation for Group 3

You will not qualify if you...

No history of atrial fibrillation for Groups 1a, 1b, and 3
Pregnant women for Group 1b
Patients who did not sign consent
History of atrial fibrillation for Group 2 and 3
Left atrial enlargement or reduced heart function for Group 2
ECG abnormalities such as QRS duration over 90 ms for Group 2
Cardiac diseases except hypertension and valvulopathies for Group 2
History of stroke or transient ischemic attack for Group 2
Stroke or transient ischemic attack over age 50 for Group 3
Patients who did not sign consent for all groups

Research Team

Philippe CHEVALIER, PU-PH

Elodie MOREL

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Biological Bank for Research on Atrial Fibrillation and Stroke Including Genetic Studies and Patient Data Collection

On this page

AI-Summary

What this Trial Is About

Brief Title

Who Can Participate

Eligibility Criteria

Research Team

Not the Right Trial for You?

On this page

Who Can Participate

Eligibility Criteria