Actively Recruiting

Age: 40Years +
All Genders
NCT03774758

Biomarkers for Risk Stratification in Lung Cancer

Led by University of California, San Francisco · Updated on 2025-03-20

590

Participants Needed

3

Research Sites

419 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

N

Northern California Institute of Research and Education

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a prospective observational study that will follow patients who undergo lung cancer screening at the San Francisco VA Medical Center, University of California, San Francisco (UCSF) Medical Center, and the San Francisco General Hospital. The proposed study will comprise of two primary populations to determine the ctDNA assay performance in a variety of clinical settings.

CONDITIONS

Official Title

Biomarkers for Risk Stratification in Lung Cancer

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 240 years
  • Ability to understand and provide written informed consent
  • Willingness to comply with study protocols and provide blood samples
  • Willingness to complete 3-year clinical follow up
Not Eligible

You will not qualify if you...

  • Active non-cutaneous malignancy within the past 5 years
  • Anemia with hematocrit less than 30% after first blood draw
  • Malnourishment with BMI less than 19 or albumin level less than 2.5 mg/dL if history of malnourishment
  • Severe Chronic Obstructive Pulmonary Disease (COPD) defined as Gold Stage IV
  • Unstable heart conditions including stable or unstable angina, recent myocardial infarction within 2 years, active congestive heart failure, ischemic cardiomyopathy, or complications from prior blood donation
  • Liver cirrhosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Zuckerberg San Francisco General Hospital and Trauma Center

San Francisco, California, United States, 94110

Actively Recruiting

2

San Francisco VA Medical Center

San Francisco, California, United States, 94121

Actively Recruiting

3

University of California, San Francisco

San Francisco, California, United States, 94122

Actively Recruiting

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Research Team

M

Mehrdad Arjomandi, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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