Actively Recruiting

Age: 65Years +
All Genders
NCT07435467

Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)

Led by Istituto Nazionale di Ricovero e Cura per Anziani · Updated on 2026-02-27

400

Participants Needed

3

Research Sites

63 weeks

Total Duration

On this page

Sponsors

I

Istituto Nazionale di Ricovero e Cura per Anziani

Lead Sponsor

M

Ministry of Health, Italy

Collaborating Sponsor

AI-Summary

What this Trial Is About

The BAD-GER study is a multicenter, prospective, three-arm observational study serving to validate a prognostic biomarker algorithm for mortality and hospital readmission; this algorithm will be developed through the retrospective analysis of Alzheimer's Disease and neurodegeneration biomarkers in an already available discovery cohort of 700 previously hospitalized geriatric patients.

CONDITIONS

Official Title

Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients hospitalized for acute neurological disorders including ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis, or meningitis
  • Inpatients diagnosed with major neurocognitive disorder (dementia) according to DSM-5 criteria
  • Inpatients with non-neurological diseases without dementia
  • Age 65 years or older
  • Ability to provide informed consent or have a legal representative provide consent
Not Eligible

You will not qualify if you...

  • Lack of informed consent
  • Patients with ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis, or meningitis excluded from non-neurological groups
  • Diagnosis of dementia excluded from non-neurological without dementia group

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

IRCCS INRCA Hospital

Ancona, Italy

Actively Recruiting

2

IRCCS INRCA Hospital

Fermo, Italy

Actively Recruiting

3

Policlinico Universitario

Messina, Italy

Actively Recruiting

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Research Team

A

Anna Rita Bonfigli

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER) | DecenTrialz