Actively Recruiting

Age: 40Years - 80Years
All Genders
Healthy Volunteers
ID06588920

Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson's Disease

Led by National Yang Ming Chiao Tung University · Updated on 2026-03-24

70

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating how brain activity related to inhibitory control and different executive function domains affect walking stability in people with Parkinson's disease (PD) and healthy older adults. The study focuses on understanding the link between cognitive functions and gait disturbances during dual-task walking, which is not yet well understood in PD patients. Participants include people diagnosed with idiopathic Parkinson disease and healthy older adults. The study observes cognitive function, gait performance, and brain activity through measures such as cognitive tests and electroencephalogram (EEG) recordings. The study compares these factors between those with PD and healthy older adults. Participants will undergo assessments of cognitive function and walking ability, including various gait measurements and brain activity tests like event-related potentials. These evaluations happen over one day and include tests such as the Frontal Assessment Battery, Trail Making Test, and Stroop Color and Word Test. The study aims to measure gait variability, speed, step length and width, and brain signals related to inhibitory control. Participation lasts for the duration of these assessments.

CONDITIONS

Brief Title

Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease

Who Can Participate

Age: 40Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with idiopathic Parkinson disease
  • Stable dopaminergic medication for at least 2 weeks
  • Able to walk 10 meters without aid
  • Mini-Mental Status Examination score of 24 points or higher
  • No uncorrected visual or hearing problems
  • Education level at least junior high school
  • No other diseases that may affect balance
Not Eligible

You will not qualify if you...

  • Other neurological, musculoskeletal, or cardiopulmonary disorders
  • History of brain surgery such as deep brain stimulation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - 1 day

Participants undergo assessments of cognitive function, gait performance, and brain activity using electroencephalogram.

1 visit (in-person)

Trial Site Locations

Total: 2 locations

1

National Yang Ming Chiao Tung University

Taipei, Taiwan

Actively Recruiting

2

National Yang Ming Chiao Tung University

Taipei, Taiwan

Actively Recruiting

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Research Team

Y

Yea-Ru Yang, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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