Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT04126148

Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)

Led by McGill University Health Centre/Research Institute of the McGill University Health Centre · Updated on 2024-10-24

350

Participants Needed

1

Research Sites

282 weeks

Total Duration

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AI-Summary

What this Trial Is About

The study aims to determine a diagnostic marker for regionally impaired myocardial oxygenation response in patients with suspected coronary artery stenosis.

CONDITIONS

Official Title

Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy participants over 40 years old with no significant cardiovascular or respiratory medical problems
  • Patients over 18 years old scheduled for invasive coronary angiography due to symptoms or positive tests indicating coronary artery ischemia
Not Eligible

You will not qualify if you...

  • Presence of pacemakers, defibrillating wires, implanted defibrillators, intracranial aneurysm clips, or metallic foreign bodies in the eyes
  • Known or suspected pregnancy
  • Consumption of caffeine within 12 hours before the exam
  • Regular nicotine use in the past 6 months
  • Use of vasoactive medication within 12 hours before the exam (patients only)
  • Contraindications to adenosine such as certain heart blocks, sinus node disease, asthma, or bronchoconstrictive diseases (patients only)
  • Acute Coronary Syndrome or previous coronary artery bypass surgery (patients only)
  • Myocardial infarction within the past month (patients only)
  • Clinically unstable condition (patients only)
  • Significant or uncontrolled arrhythmia (patients only)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

McGill University Health Center

Montreal, Quebec, Canada, H4A 3J1

Actively Recruiting

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Research Team

E

Elizabeth Konidis

CONTACT

A

Adonis Rodaros

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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