Physiological predictors of response to exposure, relaxation, and rescripting therapy for chronic nightmares in a randomized clinical trial.
Joanne L Davis, Jamie L Rhudy, Kristi E Pruiksma...
https://pubmed.ncbi.nlm.nih.gov/22171201/Actively Recruiting
Led by University of Tulsa · Updated on 2024-07-03
20
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to study the effects of Exposure, Relaxation, and Rescripting Therapy ERRT on chronic nightmares in adults diagnosed with bipolar disorder who have experienced trauma. This therapy has shown promise in reducing the frequency and intensity of nightmares and improving sleep quality, but it has not been tested in individuals with bipolar disorder before. The study focuses on people with bipolar disorder who also suffer from trauma-related sleep disturbances. Participants will receive ERRT-Bipolar Disorder, a behavioral therapy delivered once a week for about five weeks. Each session lasts approximately two hours and covers topics such as education about trauma and nightmares, relaxation techniques, exposure to trauma-related nightmares, and strategies to prevent relapse. After completing therapy, participants will be asked to complete follow-up assessments at one week, three months, and possibly one year after treatment ends. During the study, participants will be assessed before treatment and monitored through follow-up visits to evaluate changes in nightmare frequency and PTSD symptoms. The main outcome measured is the change in nightmare frequency over the past week at various time points. Secondary outcomes include changes in PTSD symptoms assessed by clinicians. The total participation time includes the treatment period and follow-up assessments to track therapy effects over time.
CONDITIONS
Brief Treatment for Trauma Nightmares in Trauma-exposed Adults With Bipolar Disorder
J
Joanne L Davis, PhD
L
Lucia D Villarreal, MS
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University of Tulsa
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | ERRT‑Bipolar Disorder | Imagery Rehearsal Therapy |
|---|---|---|
| What it is | A brief behavioral therapy combining psychoeducation, relaxation, trauma‑nightmare exposure, and rescripting delivered in five weekly sessions | A psychological technique involving recalling and rewriting nightmare content to reduce frequency and distress |
| Role in trial | The single therapy delivered to all study participants | Not studied in this trial; provided as external context |
| Primary use | To reduce trauma‑related nightmare frequency and severity in bipolar‑disorder patients | To reduce frequency and distress of trauma‑related nightmares |
| How it is given or performed | Individual weekly sessions involving trauma‑nightmare exposure, relaxation, rescripting, and relapse prevention | Guided recall and rewriting of nightmares during therapy sessions |
| Evidence status | Evidence still emerging; trial will assess impact in bipolar‑disorder population | Supported by behavioral treatment guidelines for reducing nightmares in trauma‑exposed individuals |
| Important risks | Potential for increased distress during trauma exposure, but safety data not published yet | Minimal risks; may involve temporary emotional discomfort during nightmare processing |
| Important limitations | Single‑group design without control group limits conclusions about efficacy | Effectiveness data largely from general trauma populations not specific to bipolar disorder |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 5 weeks
Participants receive weekly behavioral therapy sessions focused on exposure, relaxation, and rescripting techniques to reduce chronic trauma nightmares and sleep disturbances associated with bipolar disorder.
5 weekly visits (in-person), each lasting about two hours
Duration - Up to 1 year after treatment
Participants complete follow-up assessments to evaluate changes in nightmare frequency and PTSD symptoms after treatment.
2 to 3 visits (in-person) at 1 week, 3 months, and potentially 1 year post-treatment
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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Joanne L Davis, Jamie L Rhudy, Kristi E Pruiksma...
https://pubmed.ncbi.nlm.nih.gov/22171201/University of Tulsa
Lead Sponsor