Chronic Total Occlusion Percutaneous Coronary Intervention: Evidence and Controversies.
Peter Tajti, Emmanouil S Brilakis
https://pubmed.ncbi.nlm.nih.gov/29330258Actively Recruiting
Led by Sandwell & West Birmingham Hospitals NHS Trust · Updated on 2024-08-30
100
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are investigating the relationship between calcification characteristics seen on Computed Tomography Coronary Angiography (CTCA) and the outcomes of Percutaneous Coronary Intervention (PCI) in patients with chronic total occlusion (CTO) of the coronary artery. This observational study focuses on patients who underwent CTO PCI attempts and had CTCA scans at the study center within the last five years. The study aims to understand how calcification affects the success of PCI procedures and the use of calcium modification tools. The study involves reviewing medical records and imaging of patients who had both CTO PCI attempts and CTCA. Characteristics of calcification such as location, density measured in Hounsfield units, and quantity in the CTO will be analyzed and correlated with PCI success or failure. The study will also assess how calcium modification tools were used during PCI and their relationship to the severity of calcification. Statistical analyses will compare demographic and procedural data with calcification features and PCI outcomes. Participants will have their CTCA images and PCI reports reviewed retrospectively after providing consent through mailed forms. Researchers will analyze baseline patient data, calcification details, and procedural results. The main outcome measure is the correlation between calcification characteristics and PCI success or failure within 24 hours. Secondary measures include evaluating the role of calcium modifying tools relative to calcification severity. Participation involves no new treatment or intervention and is based on existing clinical data collected over the past five years.
CONDITIONS
Calcification on CTCA of a CTO and PCI Outcomes
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
No in-person visits; consent and information are exchanged by mail and telephone.
Duration - Up to 24 hours
Participants' CTCA images and PCI procedure data are reviewed and analyzed for characteristics of calcification and procedural outcomes.
No additional visits; data review is conducted remotely.
Total: 1 location
1
Birmingham City Hospital, Sandwell and West Birmingham NHS Trust
Birmingham, West Midlands, United Kingdom, B18 7QH
Actively Recruiting
V
Vinoda Sharma, FRCP
K
Kelly Hard
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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