Actively Recruiting

Age: 0 - 21Years
All Genders
NCT04903782

Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer

Led by Sydney Children's Hospitals Network · Updated on 2022-11-04

270

Participants Needed

3

Research Sites

379 weeks

Total Duration

On this page

Sponsors

S

Sydney Children's Hospitals Network

Lead Sponsor

C

Children's Cancer Institute Australia

Collaborating Sponsor

AI-Summary

What this Trial Is About

Assessment of the utility of family-based (trio) whole-genome sequencing for cancer predisposition testing in sequential newly diagnosed paediatric and adolescent cancer patients

CONDITIONS

Official Title

Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer

Who Can Participate

Age: 0 - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • New diagnosis of malignancy
  • Age 21 years or younger
  • Written informed consent
  • Participants aged 12 years or older (for psychosocial component)
  • Parent or caregiver of participants (for psychosocial component)
  • Healthcare professionals involved in care of enrolled patients (for psychosocial component)
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 3 locations

1

John Hunter Children's Hospital

Newcastle, New South Wales, Australia, 2305

Actively Recruiting

2

Sydney Children's Hospital

Sydney, New South Wales, Australia, 2031

Actively Recruiting

3

The Children's Hospital at Westmead

Sydney, New South Wales, Australia, 2145

Actively Recruiting

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Research Team

C

Clinical Trials Manager

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer | DecenTrialz