Study on How Regular Use of Cannabidiol CBD Affects Stress Response in Adults Aged 21 to 70

What this Trial Is About

Researchers are studying how regular use of cannabidiol CBD affects the bodys psychobiological response to acute stress. The study compares adults who regularly use CBD with those who do not, aiming to understand the effects on stress, anxiety, and physiological reactions. Information on factors related to CBD use, including tobacco consumption, will also be gathered. Participants will undergo a behavioral stress intervention that includes preparing and delivering a speech, performing a mental arithmetic task, and completing a cold pressor task by submerging their hand in ice water. The study includes both CBD users and non-users for comparison. Throughout the study, participants will be assessed for changes in subjective feelings such as stress and anxiety, as well as physiological measures including cardiovascular activity and cortisol levels over a 2.5-hour period. The study will monitor these responses to better understand how CBD use relates to stress mechanisms. Participation spans the duration of the stress tasks and associated assessments.

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms