Actively Recruiting

Phase Not Applicable
Age: 21Years - 70Years
All Genders
Healthy Volunteers
NCT07069478

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

Led by University of Minnesota · Updated on 2025-07-16

125

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to determine the effects of regular cannabidiol (CBD) use on the psychobiological mechanisms of the stress response. This will be achieved by comparing acute stress responses of adults who either use or do not use CBD regularly. Correlates of CBD use, including tobacco use, will be collected.

CONDITIONS

Official Title

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

Who Can Participate

Age: 21Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults who are relatively healthy and aged 21-70 years.
  • Must keep a normal sleep schedule (sleep during nighttime, awake during daytime).
  • Must either (1) use CBD daily/regularly or (2) not use CBD regularly.
Not Eligible

You will not qualify if you...

  • Participated in previous acute stress studies that included a similar stress induction.
  • Current, unstable major psychiatric disorder or medical condition (e.g., uncontrolled hypertension above 160/100).
  • Self-reported current pregnancy.
  • Self-reported current use of illicit substances (other than cannabis).
  • Non-compliance with instructions for study visit (abstinence from alcohol, caffeine, physical activity, etc.).
  • Students of the principal researcher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Minnesota

Minneapolis, Minnesota, United States, 55455

Actively Recruiting

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Research Team

S

Stress and Resilience Research Labs

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms | DecenTrialz