Actively Recruiting
Cardiac Biomarkers for the Quantification of Myocardial Damage After Cardiac Surgery
Led by Jena University Hospital · Updated on 2025-09-26
100
Participants Needed
5
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the study is to clarify whether the perioperative release of the cardiac biomarkers troponin I, troponin T and CK-MB consistently correlate with visualizable myocardial damage, and to what extent these biomarkers are comparable by means of their kinetics and dynamics. Due to the uncertainty regarding the validity of cardiac biomarkers in the diagnosis of myocardial infarction, the answer to these questions could have a considerable influence on internationally valid guidelines and definitions. International studies, especially in the field of coronary surgery and coronary artery disease treatment refer to these definitions, in particular, the adequate treatment of affected patients is directly dependent on them.
CONDITIONS
Official Title
Cardiac Biomarkers for the Quantification of Myocardial Damage After Cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Indication for isolated aortic or mitral valve surgery
- Written informed consent
- Age 18 years or older
You will not qualify if you...
- Presence of coronary artery disease within the last 6 months
- Allergy to gadolinium
- Cochlear implant
- Deep brain stimulation
- Conditions preventing MRI (e.g., claustrophobia)
- Significantly reduced kidney function (GFR < 30 ml/min)
- Perioperative complications causing myocardial damage
- Need for additional heart surgery beyond valve procedure
- Pregnancy or lactation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Universitäts-Herzzentrum Freiburg • Bad Krozingen
Freiburg im Breisgau, Baden-Wurttemberg, Germany, 79106
Actively Recruiting
2
Universitätsklinikum Ulm
Ulm, Baden-Wurttemberg, Germany, 89081
Actively Recruiting
3
Universitätsklinikum Münster
Münster, North Rhine-Westphalia, Germany, 48149
Actively Recruiting
4
Universitätsklinikum Halle
Halle, Saxony-Anhalt, Germany, 06120
Actively Recruiting
5
Universitätsklinikum Jena
Jena, Thuringia, Germany, 07747
Actively Recruiting
Research Team
T
Tulio Caldonazo, Dr.
CONTACT
M
Marcus Winter
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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