Actively Recruiting
Cardiovascular Research in EMbarazo and MAternity (EMMA) Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum
Led by Fundacin Biomedica Galicia Sur · Updated on 2026-02-17
242
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are studying how heart rate variability (HRV) relates to changes in blood flow and heart function during pregnancy and after childbirth. This observational study aims to understand how the nervous system controls the heart throughout pregnancy, which undergoes significant cardiovascular changes. Understanding these changes is important for monitoring heart health and predicting possible complications during pregnancy and postpartum. Participants will be monitored at specific times during pregnancy—weeks 13, 27, and 41—and at 1, 3, 6, and 12 months after giving birth. The study involves measuring many different heart and blood pressure indicators, including RR intervals, heart rate turbulence, blood pressure, cardiac output, and vascular resistance. Researchers will also assess physical activity, anxiety, depression, and pregnancy-related health events during these periods. Participants will have regular assessments involving heart rate and blood pressure measurements, blood tests for pregnancy-related proteins, and questionnaires about physical activity and mental health. These evaluations will help researchers track cardiovascular adaptations and health outcomes over time. The study includes data collection on hospitalizations and pregnancy complications, extending up to one year postpartum, to provide a comprehensive view of cardiovascular health changes.
CONDITIONS
Brief Title
Cardiovascular Research in EMbarazo and MAternity (EMMA). Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years of age
- Pregnant from the third month of gestation
- No pre-existing cardiovascular disease
- Good cognitive level
- Signed informed consent
You will not qualify if you...
- Diabetes mellitus
- Hyperthyroidism
- Hypothyroidism
- Chronic hypertension diagnosed before pregnancy
- Heart failure
- Ischemic heart disease or malignant ventricular arrhythmias
- Exercise-induced ischaemia
- Unstable angina
- Disease not susceptible to revascularization
- Associated valvular heart disease
- Chronic kidney disease
- Degenerative neurological condition
- Brain aneurysms
- Arteriovenous malformations
- History of transient cerebral infarction
- Migraines diagnosed
- Epilepsy
- Brain or spinal cord injury
- Tumors
- Diseases of the respiratory tract
- Diseases of lung tissue
- Diseases of pulmonary circulation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - From pregnancy week 13 through 12 months postpartum
Participants undergo assessments of heart rate variability and blood pressure during pregnancy and postpartum to observe cardiovascular adaptations.
Visits at pregnancy weeks 13, 27, 41 and postpartum months 1, 3, 6, and 12
Trial Site Locations
Total: 1 location
1
Hospital Alvaro Cunqueiro
Vigo, Pontevedra, Spain, 36312
Actively Recruiting
Research Team
A
Alicia González Represas
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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