Observational Study of Cancer Treatment and Outcomes in Children, Adolescents, and Young Adults in Low- and Middle-Income Countries

What this Trial Is About

Cancer is a major cause of illness and death among children, adolescents, and young adults, especially in low- and middle-income countries where timely diagnosis and treatment are often limited. This study follows young cancer patients in these settings to understand their treatment outcomes and challenges, aiming to improve access to care and results in resource-limited areas. It is a prospective, multicenter observational study that does not change or add experimental treatments. Participants include children, adolescents, and young adults diagnosed with cancer who receive routine care at participating hospitals in low- and middle-income countries. The study observes patients as a single cohort without assigning experimental treatments, with all medical care provided according to local standard practice. Researchers collect data on clinical outcomes, treatment failure, toxicity, and social factors affecting care. Participants will be followed from enrollment through 36 months of follow-up. Data will be gathered from medical records and questionnaires about access to care and social aspects affecting treatment. The study measures treatment failure and toxicity as primary outcomes and tracks secondary outcomes throughout the follow-up period. This observational study aims to provide insights into cancer care challenges and outcomes in low- and middle-income countries, with no changes to the usual care participants receive.

CAYA Cancer Prospective Cohort Study