Why primary care practices should become digital health information hubs for their patients.
Aaron Baird, Samantha Nowak
https://pubmed.ncbi.nlm.nih.gov/25421733/Actively Recruiting
Led by University of California, San Francisco · Updated on 2025-10-31
200
Participants Needed
1
Research Sites
8 weeks
Total Duration
Researchers are evaluating a new health behavior change system designed to help adolescents reduce risky behaviors, particularly alcohol use. This study focuses on using advanced machine learning and interactive narrative technology to personalize behavior change experiences for teens aged 15 to 17. The goal is to improve adolescent preventive health by integrating these tools into clinical care and extending the reach of healthcare providers. The intervention, called CHANGEGRADIENTS, is a web-based interactive tool that delivers personalized behavior change stories through a virtual environment. Adolescents will first watch a brief introductory video during their clinic visit and then receive a link to access weekly interactive narratives at home over a four-week period. The study compares this intervention with usual care provided at the clinic. Participants will engage with the system at home using personal devices like laptops or tablets, while also receiving standard clinic visits. The research team will measure outcomes including alcohol use over 30 days, self-efficacy using a specialized assessment tool, and adolescent-reported quality of care immediately after their clinic visit. The study aims to assess the impact of the intervention on adolescent behavior and health outcomes over a one-month period.
CONDITIONS
ChangeGradients: Promoting Adolescent Health Behavior Change
E
Elizabeth M Ozer, PhD
A
Alison S Giovanelli, PhD
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University of California, San Francisco
Lead Sponsor
North Carolina State University
Collaborating Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | ChangeGradients (Interactive Behavioral Program) | Usual Care (Standard Clinic Visit) |
|---|---|---|
| What it is | A digital, interactive behavioral change program delivered through a web-based platform using narrative-centered experiences. Adolescents engage with tailored content during their primary care well-visit. | Standard clinical care provided during a pediatric well-visit by primary care clinicians. No interactive behavioral tool is introduced. |
| Role in the trial | Assessed for its effectiveness in improving alcohol use, self-efficacy, and health behaviors in at-risk adolescents by adding an interactive digital experience during care. | Serves as the control group representing current standard practice in adolescent risk screening during a well-visit. |
| Primary use | Used to support and motivate healthy behavior change around alcohol use, self-efficacy, and risk-taking in adolescents during clinical encounters. | To provide routine healthcare, including risk screening and guidance, as typically delivered in adolescent primary care visits. |
| How it is given or performed | Adolescents interact with the ChangeGradients program during their medical visit using an online platform, receiving personalized and narrative-centered digital sessions. | Participants receive standard risk screenings and clinician advice during their well-visit without additional digital support. |
| Evidence status | Efficacy of ChangeGradients for behavioral change in adolescents is under active investigation in this trial. Broader literature supports digital health interventions as promising but highlights the need for high-quality evidence in clinical practice. | Usual care with clinician-led risk screening, advice, and motivational interviewing is established in primary care and supported by external evidence to modestly reduce risky behaviors in adolescents. |
| Important limitations | Clinical effectiveness is currently unproven for this setting. Real-world engagement and behavioral outcomes for digital interventions in adolescents require further study. No trial results are yet available. | Standard clinic visits may not consistently identify or address risk behaviors. Time constraints or clinician training may limit impact, and not all adolescents engage with traditional counseling methods. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 4 weeks
Participants engage with the CHANGEGRADIENTS interactive web-based behavior change system at home over a course of four weeks.
1 clinic visit to introduce the intervention and weekly use at home
Duration - Up to 30 days after baseline
Participants complete assessments of alcohol use, self-efficacy, and quality of care immediately following the baseline clinic visit and after the 4-week intervention period.
1 follow-up assessment visit
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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https://pubmed.ncbi.nlm.nih.gov/28011064/E M Ozer, A Bandura
https://pubmed.ncbi.nlm.nih.gov/2324938/Elizabeth M Ozer, Sally H Adams, Joan K Orrell-Valente...
https://pubmed.ncbi.nlm.nih.gov/22018561/University of California, San Francisco
Lead Sponsor
North Carolina State University
Collaborating Sponsor