Actively Recruiting
Characterization of Exosomes Platelets-released
Led by Centro Cardiologico Monzino · Updated on 2024-03-12
175
Participants Needed
1
Research Sites
312 weeks
Total Duration
On this page
Sponsors
C
Centro Cardiologico Monzino
Lead Sponsor
F
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Collaborating Sponsor
AI-Summary
What this Trial Is About
Extracellular vesicles (EVs) play a key role in cell-to-cell communication. They are small vesicles that contain rich molecular cargo. Recently, they have been proposed as biomarkers for clinical diagnostics. EVs include three classes: small EVs (exosomes), large EVs (microparticles), and apoptotic bodies. Platelet-derived EVs (PEVs) are the most abundant class in human blood and can actively participate in numerous physiological and pathological processes. The information about the role of platelet exosomes in cardiovascular disease and the effect of antiplatelet agents on their release and content is very limited.
CONDITIONS
Official Title
Characterization of Exosomes Platelets-released
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects without known pathologies
You will not qualify if you...
- Individuals with gastrointestinal diseases
- Individuals with history of hepatic diseases
- Individuals with history of urogenital diseases
- Individuals with history of hematological diseases
- Individuals with history of immunological diseases
- Individuals with history of renal diseases
- Individuals with history of metabolic diseases
- Individuals with history of respiratory diseases
- Individuals with history of cancer
- Individuals with history of cardiovascular disease
- Individuals having permanent organ damage
- Individuals with major trauma in the last 6 months prior to enrollment
- Individuals with surgery in the last 6 months prior to enrollment
- Individuals taking medication in the 15 days prior to enrolment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
Actively Recruiting
Research Team
S
Silvia S Barbieri, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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