Actively Recruiting

Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT03255928

Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)

Led by Scientific Institute San Raffaele · Updated on 2025-05-15

60

Participants Needed

1

Research Sites

496 weeks

Total Duration

On this page

Sponsors

S

Scientific Institute San Raffaele

Lead Sponsor

U

Università Vita-Salute San Raffaele

Collaborating Sponsor

AI-Summary

What this Trial Is About

Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane oxygenator (ECMO), Ventricular Assist Device (VAD) will be enrolled in the study. Aim of the study is to evaluate the patients' haemostatic and coagulation profile, how it interacts with the support device as well as the effect of antithrombotic drugs. From these data, it will be possible to derive the mechanisms triggering post-implant thromboembolic/hemorrhagic complications and to identify potential therapeutic targets.

CONDITIONS

Official Title

Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • All consenting patients candidates for short-term (Impella, ECMO) or durable (LVAD) mechanical circulatory support device implantation
  • All consenting patients that are implanted with short-term (Impella, ECMO) or durable (LVAD) mechanical circulatory support device
Not Eligible

You will not qualify if you...

  • Patients younger than 18 years old

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

San Raffaele Scientifc Institute - Cardiothoracic Intensive Care Unit

Milan, MI, Italy, 20132

Actively Recruiting

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Research Team

F

Filippo Consolo, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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