Actively Recruiting
Characterizing Disease Biology, Treatment Patterns and Toxicity in Older Adults With Advanced Hepatocellular Carcinoma
Led by The University of Texas Health Science Center at San Antonio · Updated on 2026-01-08
84
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting an observational study involving 84 participants newly diagnosed with unresectable, advanced hepatocellular carcinoma (HCC). The study focuses on understanding disease characteristics, treatment patterns, and toxicity, especially in older adults aged 65 and above, by using geriatric assessment tools and collecting markers related to aging and treatment side effects. Participants aged 65 years or older will undergo Comprehensive Geriatric Assessment before receiving their standard interventional treatment. The study groups include those 65 years and older and those younger than 65. Observations include treatment toxicities and cellular aging changes related to treatment outcomes. Participants will be monitored at several time points including screening, and months 1, 2, 4, 6, 8, 10, and 12. Researchers will collect data on disease progression, treatment patterns, and adverse events. This monitoring aims to help develop personalized treatment plans for older adults based on the study findings. The total participation lasts up to 12 months with regular assessments.
CONDITIONS
Brief Title
Characterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically or radiographically (CT or MRI) confirmed newly diagnosed hepatocellular carcinoma
- Age 18 years and older
- Patients with advanced, unresectable HCC as determined by the treating physician
You will not qualify if you...
- Patients with resectable HCC who are still candidates for locoregional therapy
- Patients receiving prior systemic or locoregional therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 months
Participants undergo assessments including Comprehensive Geriatric Assessment and observation of disease characteristics, treatment patterns, and toxicities over time.
Visits at Month 1, Month 2, Month 4, Month 6, Month 8, Month 10, and Month 12
Trial Site Locations
Total: 1 location
1
Mays Cancer Center
San Antonio, Texas, United States, 78229
Actively Recruiting
Research Team
M
Maggie Tomasini, MPH
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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