Study of Disease Patterns, Treatment, and Side Effects in Adults 18 and Older with Advanced Hepatocellular Carcinoma Including Special Assessment for Participants 65 Years and Older

What this Trial Is About

Researchers are conducting an observational study involving 84 participants newly diagnosed with unresectable, advanced hepatocellular carcinoma HCC. The study focuses on understanding disease characteristics, treatment patterns, and toxicity, especially in older adults aged 65 and above, by using geriatric assessment tools and collecting markers related to aging and treatment side effects. Participants aged 65 years or older will undergo Comprehensive Geriatric Assessment before receiving their standard interventional treatment. The study groups include those 65 years and older and those younger than 65. Observations include treatment toxicities and cellular aging changes related to treatment outcomes. Participants will be monitored at several time points including screening, and months 1, 2, 4, 6, 8, 10, and 12. Researchers will collect data on disease progression, treatment patterns, and adverse events. This monitoring aims to help develop personalized treatment plans for older adults based on the study findings. The total participation lasts up to 12 months with regular assessments.

Characterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma