Actively Recruiting

Age: 16Years +
All Genders
NCT02579278

Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion

Led by Imperial College London · Updated on 2024-10-17

100

Participants Needed

3

Research Sites

734 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study does not involve randomization or treatment. Eligible patients have colorectal adenocarcinoma with no metastases eligible for curative surgery. A pre operative staging scan must have been completed within 6 weeks prior to surgery. Two x 20ml blood samples will be taken from each patient, one prior to and one during or within 24hrs after surgery. Patients are annually followed up to 3 years.

CONDITIONS

Official Title

Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion

Who Can Participate

Age: 16Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a biopsy-confirmed colorectal adenocarcinoma
  • Be eligible for curative surgery
  • Have no metastatic disease on CT scan
  • Have completed pre-operative staging scan within six weeks prior to surgery
  • Have provided written informed consent to participate in the study
  • Be aged 16 years or over
Not Eligible

You will not qualify if you...

  • Have metastatic disease (including resectable liver metastases)
  • Have a synchronous second malignancy
  • Are contraindicated for any imaging able to determine EMVI status

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Queen Elizabeth the Queen Mother Hospital

Margate, Kent, United Kingdom, CT9 4AN

Actively Recruiting

2

St Mary's Hospital (Imperial)

Hammersmith, London, United Kingdom, W2 1NY

Actively Recruiting

3

Royal Marsden Hospital NHS Foundation Trust

Sutton, Surrey, United Kingdom, SM2 5PT

Actively Recruiting

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Research Team

C

Caroline Martin

CONTACT

S

Syvella Ellis

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion | DecenTrialz