Long-Term Follow-Up Study on Outcomes and Recurrence Risk After Treatment of Cardiac Arrhythmias at University Heart Center Hamburg

What this Trial Is About

Researchers are conducting a prospective clinical cohort study called TRUST to better understand long-term outcomes and factors that predict recurrence in patients treated for cardiac arrhythmias or those at high risk for arrhythmias. This study focuses on conditions such as atrial fibrillation, ventricular tachycardia, and other serious arrhythmias that contribute significantly to illness and death, especially in aging populations. It aims to collect detailed clinical and procedural information alongside systematic biobanking to enable precise patient characterization. Participants will be enrolled at a single tertiary care center specializing in heart conditions. The study involves collecting routine follow-up data and detailed information about treatments, including medications, devices, and interventions used to manage arrhythmias. Biosamples will be collected for molecular analysis, and digital tools will be used to capture clinical data and monitor heart rhythms over time. During the study, participants will undergo systematic rhythm monitoring with digital devices and regular clinical assessments over a five-year follow-up period. Researchers will evaluate outcomes such as cardiovascular mortality, stroke, heart failure hospitalizations, new arrhythmias, and quality of life. Safety outcomes including complications from rhythm control therapies and overall survival will also be monitored. The study aims for near-complete inclusion of eligible patients treated at the center to gather robust real-world data.

Clinical Cohort Study - TRUST