Actively Recruiting

Phase 2
Phase 3
Age: 60Years +
All Genders
NCT05357690

A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation

Led by Mayo Clinic · Updated on 2025-05-14

220

Participants Needed

1

Research Sites

188 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal, fast beating of the upper chambers of the heart. Stellate ganglion blockade has shown to decrease other types of abnormal heart rhythms as well as decrease the chance of atrial fibrillation.

CONDITIONS

Official Title

A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient presenting for cardiac surgery at the Mayo Clinic in Rochester, Minnesota
  • Scheduled to undergo mitral or aortic valve surgery with or without coronary artery bypass grafting
Not Eligible

You will not qualify if you...

  • History of permanent atrial fibrillation
  • Left or right ventricular assist device implantation or explantation
  • Procedures not requiring cardiopulmonary bypass
  • Procedures requiring deep hypothermic circulatory arrest
  • Active infection or sepsis
  • Pre-operative immunosuppressive medication use including steroids
  • Pre-operative anti-arrhythmic medication use aside from beta-blockers
  • Immunodeficiency syndrome
  • Known neurologic disorder
  • Requirement for left internal jugular central line placement

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
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Trial Site Locations

Total: 1 location

1

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation | DecenTrialz