Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07592325

Clinical Evaluation of the Access Socket Flexible Socket for Transtibial Prosthesis

Led by Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est · Updated on 2026-05-18

25

Participants Needed

5

Research Sites

26 weeks

Total Duration

On this page

Sponsors

U

Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est

Lead Sponsor

I

Institution Nationale des Invalides

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a new type of prosthetic socket called the Access Socket (AS) for adults with transtibial amputation, which affects the lower leg below the knee. This study compares the AS to the standard rigid socket (RS) to see if it improves comfort, function, and mobility. The AS combines rigid carbon-fiber areas with flexible urethane-resin zones to enhance comfort and pressure distribution while maintaining support for walking. This study is a multicenter, randomized, open-label crossover trial involving 25 adults. Participants will wear each type of socket for about 4 weeks, after a 1-2 week adaptation period, in a randomized order. One group starts with the RS and then switches to the AS, while the other group starts with the AS and then switches to the RS. Both sockets are made from the same mold to ensure the same internal shape; the difference lies in the materials used. The study includes an optional follow-up visit one month after the second socket period for those who choose to keep the AS. During the study, participants will attend four visits over approximately 14 to 21 weeks. Researchers will assess function using the Patient Specific Functional Scale (PSFS) at the end of each socket wear period. Other measures include comfort, satisfaction, psychosocial adjustment, mobility, and prosthesis utility. Safety and patient choice of socket at study completion will also be monitored. Participants must be adults with transtibial amputation currently using a rigid socket and able to provide informed consent.

CONDITIONS

Brief Title

Clinical Evaluation of the Access Socket Flexible Socket for Transtibial Prosthesis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Unilateral or bilateral transtibial amputation
  • Currently fitted with a definitive carbon rigid socket
  • Any residual-limb shape
  • Any cause of amputation
  • Able to understand simple instructions, read, write, and provide informed consent, or accompanied by a trusted person if unable to read/write
  • Provided free written informed consent
  • Aged 18 years or older
  • Affiliated to a social security system
Not Eligible

You will not qualify if you...

  • Use of hydroalcoholic solution for socket donning
  • Currently fitted with a provisional socket
  • Neurological condition limiting activity participation
  • Orthopedic condition limiting activity participation
  • Pregnant or breastfeeding women
  • Minors
  • Persons unable to express consent or not under legal protection
  • Persons under guardianship, curatorship, or judicial protection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Approximately 10 to 12 weeks

Participants wear one type of prosthetic socket for 4 weeks, followed by a switch to the other socket type with 1 to 2 weeks of adaptation and another 4 weeks of wear.

3 visits: one at inclusion, one after the first socket period, and one after the second socket period

Follow-up

Duration - 1 month

Participants may have an optional follow-up visit one month later if they elect to keep the Access Socket.

1 optional visit (in-person)

Trial Site Locations

Total: 5 locations

1

Hôpital National d'Instruction des Armées (HNIA) Percy

Clamart, France, 92140

Actively Recruiting

2

Hôpital Filieris de Freyming-Merlebach

Freyming-Merlebach, France, 57804

Actively Recruiting

3

CHU Grenoble Alpes - Hôpital Sud

Grenoble, France, 38434

Actively Recruiting

4

Institut Régional de Médecine Physique et de Réadaptation (IRR) - Filière Locomoteur

Nancy, France, 54000

Actively Recruiting

5

Insititution Nationale des Invalides

Paris, France, 75007

Actively Recruiting

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Research Team

I

Isabelle Loiret, MD

J

Jonathan Pierret, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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