Actively Recruiting
Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms
Led by Mayo Clinic · Updated on 2026-02-23
150
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are collecting data on patients treated with open surgical repair (OR) for complex aortic aneurysms (CAAs) in this prospective, non-randomized, single-center study. The study focuses on patients needing OR for abdominal and thoracoabdominal aneurysms or chronic aortic dissections. The goal is to understand outcomes such as quality of life and major adverse events after surgery. The choice of prosthetic graft and surgical technique is determined by the vascular surgeon based on disease extent, with no difference in surgical methods assumed. Patients will undergo OR performed by Mayo Clinic vascular surgeons. Data will be gathered on clinical presentation, imaging, surgery details, ICU and hospital stay lengths, mortality, complications, reintervention, and aneurysm rupture. Participants will complete the SF-36 health survey and a CAA-specific questionnaire before surgery and at 4 months, 1 year, 3 years, and 5 years after surgery. Follow-up includes office visits, mailed questionnaires, and telephone interviews if responses are not received within six weeks. The main outcome measured is change in health-related quality of life over five years using the SF-36 tool.
CONDITIONS
Brief Title
Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing elective, emergent, or urgent open surgical repair for complex aortic aneurysms
- Abdominal aortic aneurysms not eligible for endovascular repair, including infrarenal with complex morphology, short neck infrarenal, juxtarenal, or suprarenal aneurysms
- Thoracoabdominal aortic aneurysms (Type I-IV)
- Chronic aortic dissections
- Adults aged 18 years or older
You will not qualify if you...
- Patients who refuse to participate in the study
- Patients younger than 18 years
- Pregnant or breastfeeding patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Hospitalization period following surgery
Participants undergo open surgical repair for complex aortic aneurysms performed by vascular surgeons. Immediate post-operative care includes hospitalization and ICU stay as needed.
Visits during hospitalization and ICU stay
Duration - Up to 5 years post-operatively
Participants complete health-related quality of life questionnaires and attend office visits or respond by mail/telephone to assess recovery and outcomes over time.
Office visits or questionnaires at 4 months, 1 year, 3 years, and 5 years post-surgery
Trial Site Locations
Total: 1 location
1
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
J
Jenny Haen
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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