Actively Recruiting

All Genders
NCT06295965

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

Led by University of Washington · Updated on 2026-04-17

2000

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

Sponsors

U

University of Washington

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is being done to investigate clonal hematopoiesis and therapy-emergent myeloid neoplasms in patients with ovarian or other solid cancers. Researchers want to identify risk factors for developing these blood cancers as well as if there is/are a genetic/environmental component(s) to developing blood cancer.

CONDITIONS

Official Title

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have or have had ovarian, peritoneal, or fallopian tube carcinoma with a life expectancy of greater than 6 months
  • Have completed or plan to complete at least 5 cycles of platinum-based chemotherapy
  • Have or have had a solid tumor diagnosis with either at least 4 months of exposure to a PARP inhibitor or a diagnosis of a blood disorder including clonal hematopoiesis of indeterminate potential, cytopenia of unknown significance, or therapy-related myeloid neoplasm
Not Eligible

You will not qualify if you...

  • Life expectancy less than 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, United States, 98109

Actively Recruiting

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Research Team

S

Swisher Lab Research Coordinators

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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