Actively Recruiting
A Cohort Study of Hereditary Ovarian Cancer Risk Prediction Models and Pathogenesis Exploration
Led by Peking University Third Hospital · Updated on 2025-06-18
1000
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this project is to establish a bidirectional multicenter cohort of hereditary ovarian cancer and to describe the clinicopathologic features of hereditary ovarian cancer patients in our country. The risk prediction model of ovarian cancer for Chinese was established by following-up analysis of clinical and pathological information, genetic test results and detailed family history, to predict the risk of cancer in first-degree relatives of carriers of pathogenic/suspected pathogenic mutations, and to guide the intervention management of high-risk population of cancer. The study will identify novel tumor-causing mutations/predisposing genes by gene sequencing in a special family with hereditary tumor.
CONDITIONS
Official Title
A Cohort Study of Hereditary Ovarian Cancer Risk Prediction Models and Pathogenesis Exploration
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of epithelial ovarian cancer
- Age 18 years or older
- Clear pathological diagnosis
- Genetic test confirming germ line pathogenic or suspected pathogenic mutations according to ACMG standards
You will not qualify if you...
- Diagnosis of non-epithelial ovarian cancer confirmed by pathology
- No genetic testing performed
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Peking University Third Hospital
Beijing, Beijing Municipality, China, 100000
Actively Recruiting
Research Team
Y
Yuan Li, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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